Selective blockade of 5-HT2A receptors attenuates the increased temperature response in brown adipose tissue to restraint stress in rats.

@article{Ootsuka2008SelectiveBO,
  title={Selective blockade of 5-HT2A receptors attenuates the increased temperature response in brown adipose tissue to restraint stress in rats.},
  author={Youichirou Ootsuka and William Walter Blessing and Eugene Nalivaiko},
  journal={Stress},
  year={2008},
  volume={11 2},
  pages={125-33}
}
Previous studies have demonstrated that 5-HT2A receptors may be involved in the central control of thermoregulation and of the cardiovascular system. Our aim was to test whether these receptors mediate thermogenic and tachycardiac responses induced by acute psychological stress. Three groups of adult male Hooded Wistar rats were instrumented with: (i) a thermistor in the interscapular area (for recording brown adipose tissue temperature) and an ultrasound Doppler probe (to record tail blood… CONTINUE READING