Selective attenuation of isoproterenol-stimulated arrhythmic activity by a partial agonist of adenosine A1 receptor.

Abstract

BACKGROUND The goal of this study was to examine the hypothesis that a partial agonist of the adenosine A1 receptor (A1AdoR) may cause a greater attenuation of catecholamine-induced ventricular arrhythmic activity than of contractility. METHODS AND RESULTS The effects of CVT-2759 and adenosine, a partial and a full agonist of the A1AdoR, on isoproterenol… (More)

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