Selective and reversible reduction of odor sensitivity in the rat by concanavalin A.

@article{Apfelbach1998SelectiveAR,
  title={Selective and reversible reduction of odor sensitivity in the rat by concanavalin A.},
  author={Raimund Apfelbach and Elke Weiler and W F Asselbergs and Ernest H Polak and Burton M. Slotnick},
  journal={Physiology & behavior},
  year={1998},
  volume={65 3},
  pages={513-6}
}
Rats were trained using an olfactometer to detect low concentrations of ethyl acetate (EA) or dimethyl disulphide vapor (DMDS). Concanavalin A (ConA) applied to the olfactory mucosa had no effect on ability of rats to detect low concentrations of EA but produced a marked deficit in detection in DMDS. DMDS detection performance returned to control levels 3 days after the ConA treatment. These results provide the first behavioral evidence for odor-specific inhibition by chemical modification of… CONTINUE READING