Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on U46619-induced contraction in rat aorta

@inproceedings{Sato2013SelectiveAP,
  title={Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on
U46619-induced contraction in rat aorta},
  author={Kyosuke Sato and Daisuke Chino and Tomoya Kobayashi and Keisuke Obara and Seiji Miyauchi and Yoshio Tanaka},
  booktitle={Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi},
  year={2013}
}
Inhibitory effects of docosahexaenoic acid (DHA) on blood vessel contractions induced by various constrictor stimulants were investigated in the rat thoracic aorta. The inhibitory effects of DHA were also compared with those of eicosapentaenoic acid (EPA) and linoleic acid (LA). DHA exhibited a strong inhibitory effect on the sustained contractions induced by U46619, a TXA(2) mimetic. This inhibitory effect of DHA was not affected by removal of the endothelium or by treatment with either… CONTINUE READING

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