Selective amplification by auto- and cross-catalysis in a replicating peptide system

@article{Yao1998SelectiveAB,
  title={Selective amplification by auto- and cross-catalysis in a replicating peptide system},
  author={Shao Q Yao and Indraneel Ghosh and Reena Zutshi and Jean Chmielewski},
  journal={Nature},
  year={1998},
  volume={396},
  pages={447-450}
}
Self-replication has been demonstrated in synthetic chemical systems based on oligonucleotides, peptides and complementary molecules without natural analogues. However, within a living cell virtually no molecule catalyses its own formation, and the search for chemical systems in which both auto- and cross-catalysis can occur has therefore attracted wide interest. One such system, consisting of two self-replicating peptides that catalyse each other's production, has been reported. Here we… CONTINUE READING

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