Selective alterations in GABAA receptor subtypes in human temporal lobe epilepsy.

Abstract

Temporal lobe epilepsy (TLE) is associated with impaired inhibitory neurotransmission. Studies in animal models suggest that GABA(A) receptor dysfunction contributes to epileptogenesis. To understand the mechanisms underlying TLE in humans, it is fundamental to determine whether and how GABA(A) receptor subtypes are altered. Furthermore, identifying novel… (More)

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Cite this paper

@article{Loup2000SelectiveAI, title={Selective alterations in GABAA receptor subtypes in human temporal lobe epilepsy.}, author={Fabienne Loup and Heinz Gregor Wieser and Yasuhiro Yonekawa and Adriano Aguzzi and Jean-Marc Fritschy}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2000}, volume={20 14}, pages={5401-19} }