Selective alpha 1-adrenoceptor antagonists in benign prostatic hyperplasia: rationale and clinical experience.

@article{Chapple1996SelectiveA1,
  title={Selective alpha 1-adrenoceptor antagonists in benign prostatic hyperplasia: rationale and clinical experience.},
  author={Christopher R Chapple},
  journal={European urology},
  year={1996},
  volume={29 2},
  pages={129-44}
}
Symptomatic benign prostatic hyperplasia (BPH) is a common condition in older men and has a significant impact on their daily lives. Transurethral resection of the prostate is currently the most effective remedy for BPH but is not suitable for all patients. There is now clear evidence for the efficacy of alpha-adrenoceptor antagonists, particularly selective alpha 1-adrenoceptor antagonists, in the treatment of BPH. Inhibition of alpha-adrenoceptors significantly increases urinary flow and… CONTINUE READING

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