Selective activation of corticotropin-releasing factor-2 receptors on neurochemically identified neurons in the rat dorsal raphe nucleus reveals dual actions.

@article{Pernar2004SelectiveAO,
  title={Selective activation of corticotropin-releasing factor-2 receptors on neurochemically identified neurons in the rat dorsal raphe nucleus reveals dual actions.},
  author={Luise I. M. Pernar and Andre L. Curtis and Wylie W. Vale and Jean Edouard Frederic Rivier and Rita J Valentino},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2004},
  volume={24 6},
  pages={
          1305-11
        }
}
The dorsal raphe (DR)-serotonin (5-HT) system has been implicated in stress-related psychiatric disorders. Stress may impact on this system through corticotropin-releasing factor (CRF), which densely innervates the DR. CRF binds to CRF-R1 and CRF-R2 receptors in the DR and has complex and opposing effects depending on the dose used and the endpoint examined. To clarify the impact of CRF on the DR-5-HT system, the effects of selectively activating CRF-R2 receptors (the predominant subtype) on… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 52 CITATIONS, ESTIMATED 33% COVERAGE

Corticotropin-releasing factor increases GABA synaptic activity and induces inward current in 5-hydroxytryptamine dorsal raphe neurons.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2008
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2004
2018

CITATION STATISTICS

  • 8 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2001
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Circuitry underlying regulation of the serotonergic system by swim stress.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2003
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Regulation of serotonin release in the lateral septum and striatum by corticotropin-releasing factor.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…