Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

@article{Carter1996SelectiveAO,
  title={Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.},
  author={Bruce D Carter and Christian Kaltschmidt and Barbara Kaltschmidt and Nina Offenh{\"a}user and Renate B{\"o}hm-Matthaei and P Atricka . Baeuerle and Yves Alain Barde},
  journal={Science},
  year={1996},
  volume={272 5261},
  pages={
          542-5
        }
}
Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) selectively bind to distinct members of the Trk family of tyrosine kinase receptors, but all three bind with similar affinities to the neurotrophin receptor p75 (p75NTR). The biological significance of neurotrophin binding to p75NTR in cells that also express Trk receptors has been difficult to ascertain. In the absence of TrkA, NGF binding to p75NGR activated the transcription factor nuclear factor… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 102 CITATIONS, ESTIMATED 64% COVERAGE

Nuclear Factor κB Signaling in Opioid Functions and Receptor Gene Expression

  • Journal of Neuroimmune Pharmacology
  • 2006
VIEW 13 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Roles for NF-κB in nerve cell survival, plasticity, and disease

  • Cell Death and Differentiation
  • 2006
VIEW 10 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1999
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Neural plasticity: changes with age

  • Journal of Neural Transmission
  • 2004
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Transcriptional control in myelinating glia: flavors and spices.

  • Glia
  • 2000
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1996
2019

CITATION STATISTICS

  • 13 Highly Influenced Citations

Similar Papers

Loading similar papers…