Selective activation of Ca(2+)-dependent K+ channels by novel benzimidazolone.

  title={Selective activation of Ca(2+)-dependent K+ channels by novel benzimidazolone.},
  author={S P Olesen and Elke Munch and P. Moldt and J. Drejer},
  journal={European journal of pharmacology},
  volume={251 1},
Activators and blockers of specific ion channels are important pharmacological tools for characterizing ion channels and their influence on cell function. The large-conductance Ca(2+)-dependent K+ channel (BK channel) is blocked by peptides such as charybdotoxin and iberiotoxin, but no selective activator of the channel has been described. Here we report single-channel and whole-cell patch-clamp experiments on the specific activation of BK channels in aortic smooth muscle cells with a new… CONTINUE READING
Highly Influential
This paper has highly influenced 13 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 72 extracted citations

Similar Papers

Loading similar papers…