Selective activation of β3-adrenoceptors by octopamine: comparative studies in mammalian fat cells

@article{Carpn1999SelectiveAO,
  title={Selective activation of $\beta$3-adrenoceptors by octopamine: comparative studies in mammalian fat cells},
  author={Christian Carp{\'e}n{\'e} and J Galitzky and E. Fontana and Claude Atgi{\'e} and Max Lafontan and Michel Berlan},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1999},
  volume={359},
  pages={310-321}
}
Abstract Numerous synthetic agonists selectively stimulate β3-adrenoceptors (ARs). The endogenous catecholamines, noradrenaline and adrenaline, however, stimulate all the β-AR subtypes, and no selective physiological agonist for β3-ARs has been described so far. The aim of this study was to investigate whether any naturally occurring amine can stimulate selectively β3-ARs. Since activation of lipolysis is a well-known β-adrenergic function, the efficacy and potency of various biogenic amines… Expand
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