Selective accumulation of monoclonal antibodies in the lungs after injection of cyclophosphamide into rats

The possibility of targeted transport of active drugs to particular organs and tissues has been studied for a long time. Much of the research into targeted transport of various compounds, including radioisotopes, has been undertaken with antibodies against surface antigens [1, 2]. However, Welt and co-workers used an intracellular antigen of an experimental… CONTINUE READING