Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.

Abstract

BACKGROUND Studies with c-kit mutant mast cell (MC)-deficient mice and antibody-mediated depletion of basophils suggest that both MCs and basophils can contribute to peanut-induced anaphylaxis (PIA). However, interpretation of data obtained by using such approaches is complicated because c-kit mutant mice have several phenotypic abnormalities in addition to… (More)
DOI: 10.1016/j.jaci.2013.06.008

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Cite this paper

@article{Reber2013SelectiveAO, title={Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.}, author={Laurent Lionel Reber and Thomas Marichal and Kaori Mukai and Yoshihiro Kita and Suzumi M. Tokuoka and Axel Roers and Karin Hartmann and Hajime Karasuyama and Kari Christine Nadeau and Mindy Tsai and Stephen J Galli}, journal={The Journal of allergy and clinical immunology}, year={2013}, volume={132 4}, pages={881-8.e1-11} }