Selective Radical Fluorination of Tertiary Alkyl Halides at Room Temperature.

@article{Chen2017SelectiveRF,
  title={Selective Radical Fluorination of Tertiary Alkyl Halides at Room Temperature.},
  author={He Chen and Zhonglin Liu and Ying Lv and Xinqiang Tan and Haigen Shen and Haizhu Yu and Chaozhong Li},
  journal={Angewandte Chemie},
  year={2017},
  volume={56 48},
  pages={
          15411-15415
        }
}
Direct fluorination of tertiary alkyl bromides and iodides with Selectfluor is described. The halogen-exchange fluorination proceeds efficiently in acetonitrile at room temperature under metal-free conditions and exhibits a wide range of functional group compatibility. Furthermore, the reactions are highly selective in that alkyl chlorides and primary and secondary alkyl bromides remain intact. A radical mechanism is proposed for this selective fluorination. 
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