Selective NF-kappaB inhibition, but not dexamethasone, decreases acute lung injury in a newborn piglet airway inflammation model.

@article{Bismarck2009SelectiveNI,
  title={Selective NF-kappaB inhibition, but not dexamethasone, decreases acute lung injury in a newborn piglet airway inflammation model.},
  author={Philipp von Bismarck and Karsten Klemm and Carlos-Francisco Garc{\'i}a Wist{\"a}dt and Supandi Winoto-Morbach and Stephan Sch{\"u}tze and Martin F. Krause},
  journal={Pulmonary pharmacology & therapeutics},
  year={2009},
  volume={22 4},
  pages={297-304}
}
Acute respiratory failure in neonates (e.g. ARDS, meconium aspiration pneumonitis, pneumonia) is characterized by an excessive inflammatory response, governing the migration of polymorpho-nuclear leukocytes (PMNLs) into lung tissue and causing consecutive impairment of gas exchange and lung function. Critical to this inflammatory response is the activation… CONTINUE READING