Selective MCA occlusion: a precise embolic stroke model.

  title={Selective MCA occlusion: a precise embolic stroke model.},
  author={Vincent A Dinapoli and Charles Lee Rosen and Tomoaki Nagamine and Todd J Crocco},
  journal={Journal of neuroscience methods},
  volume={154 1-2},
The present study describes a method for improving the precision and accuracy of clot placement within the middle cerebral artery (MCA) of rats, utilizing a micro-catheter and laser Doppler flowmetry. This technique reduces the size of clot needed to achieve stable occlusion with no failed embolizations and a low percentage of early recanalizations. Infarctions were consistent in both size and distribution within the MCA perfusion territory. Selective embolization in aged animals (n = 10… CONTINUE READING


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