Selective Loss of GRK2 Regulation and Its Consequences: Cerebrovascular Complications and Alzheimer disease

Abstract

Increasing evidence suggests to vascular damage as an early contributor to the development of two leading causes of age-associated dementia, namely Alzheimer disease (AD) and AD-like pathology such as stroke. This review focuses on the role of G protein-coupled receptor kinases, particularly GRK2 as they relate to dementia and how the vascular abnormalities… (More)

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Cite this paper

@inproceedings{Obrenovich2010SelectiveLO, title={Selective Loss of GRK2 Regulation and Its Consequences: Cerebrovascular Complications and Alzheimer disease}, author={Mark E. Obrenovich and Kazimierz Gąsiorowski and H{\'e}ctor Palacios and Dmitry Gokhman and Vagif B. Shadlinski and Valentin Bragin and J. Leszek and Gjumrakch Aliev}, year={2010} }