Selective Inhibitors of Protein Methyltransferases

Abstract

Mounting evidence suggests that protein methyltransferases (PMTs), which catalyze methylation of histone and nonhistone proteins, play a crucial role in diverse biological processes and human diseases. In particular, PMTs have been recognized as major players in regulating gene expression and chromatin state. PMTs are divided into two categories: protein… (More)
DOI: 10.1021/jm501234a

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Cite this paper

@inproceedings{Kaniskan2015SelectiveIO, title={Selective Inhibitors of Protein Methyltransferases}, author={H. {\"U}mit Kaniskan and Kyle David Konze and Jian Jin}, booktitle={Journal of medicinal chemistry}, year={2015} }