Selective Inhibition of Steroidogenic Enzymes by Ketoconazole in Rat Ovary Cells

Abstract

OBJECTIVE Ketoconazole (KCZ) is an anti-fungal agent extensively used for clinical applications related to its inhibitory effects on adrenal and testicular steroidogenesis. Much less information is available on the effects of KCZ on synthesis of steroid hormones in the ovary. The present study aimed to characterize the in situ effects of KCZ on… (More)
DOI: 10.4137/CMRH.S14036

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