Selective IgE deficiency, immune dysregulation, and autoimmunity.

  title={Selective IgE deficiency, immune dysregulation, and autoimmunity.},
  author={Eli Magen and Menachem Schlesinger and Michael David and Itzhak Ben-Zion and Daniel A. Vardy},
  journal={Allergy and asthma proceedings},
  volume={35 2},
Selective IgE deficiency (IgED) is currently defined as a significant decrease in serum levels of IgE (<2 kIU/L) in a patient whose other immunoglobulin levels are normal. There are no published large-scale epidemiological studies regarding the prevalence of and clinical features of IgED. In the population-based case-control study, we investigated clinical and laboratory characteristics of patients with IgED. Case samples were drawn from all subjects (n = 18487), with serum total IgE… CONTINUE READING
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