Selective Gene Expression by Postnatal Electroporation during Olfactory Interneuron Neurogenesis

@article{Chesler2008SelectiveGE,
  title={Selective Gene Expression by Postnatal Electroporation during Olfactory Interneuron Neurogenesis},
  author={Alexander T Chesler and Claire E Le Pichon and Jessica H. Brann and Ricardo C Araneda and Dong-Jing Zou and Stuart Firestein},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={121 - 128}
}
Neurogenesis persists in the olfactory system throughout life. The mechanisms of how new neurons are generated, how they integrate into circuits, and their role in coding remain mysteries. Here we report a technique that will greatly facilitate research into these questions. We found that electroporation can be used to robustly and selectively label progenitors in the Subventicular Zone. The approach was performed postnatally, without surgery, and with near 100% success rates. Labeling was… CONTINUE READING
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