Selective Estrogen Receptor Modulators

@article{Haskell2003SelectiveER,
  title={Selective Estrogen Receptor Modulators},
  author={S. Haskell},
  journal={Southern Medical Journal},
  year={2003},
  volume={96},
  pages={469-476}
}
  • S. Haskell
  • Published 2003
  • Medicine
  • Southern Medical Journal
Because of recent concerns about the long-term risks of estrogen replacement therapy in postmenopausal women, there is growing interest in a group of compounds known as selective estrogen receptor modulators (SERMs). The SERMs bind to estrogen receptors and have tissue-specific effects that allow them to function as estrogen agonists in some tissues and estrogen antagonists in other tissues. There are four SERMs currently marketed in the United States. These include the triphenylethylenes… Expand
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17 Citations
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17 Citations

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[Changes in the endometrium after tamoxifen therapy].
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Effects of 4-hydroxytamoxifen, raloxifene and ICI 182 780 on survival of uterine cancer cell lines in the presence and absence of exogenous estrogens.
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Estrogen receptor beta is a negative regulator of mammary cell proliferation
The selective estrogen receptor modulator SCH 57068 prevents bone loss, reduces serum cholesterol and blocks estrogen-induced uterine hypertrophy in ovariectomized rats
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[Effects of tamoxifen on the expression of TGF-beta and p27 proteins in polyps and adjacent endometrium in postmenopausal women].
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Estradiol and progesterone differentially regulate formalin-induced nociception in ovariectomized female rats
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Acute tamoxifen treatment increases nitric oxide level but not total antioxidant capacity and adenosine deaminase activity in the plasma of rabbits.
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Interactions of estradiol and NSAIDS on carrageenan-induced hyperalgesia
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Andrographolide prevents human breast cancer-induced osteoclastic bone loss via attenuated RANKL signaling
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Efeitos do tamoxifeno sobre a expressão das proteínas TGF-β e p27 em pólipos e endométrio adjacente de mulheres após a menopausa
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