Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer.

Abstract

We have investigated the use of a cell surface antigen as a dominant selectable marker to facilitate the detection and selection of retrovirally infected target cells. The small coding region of the human cell surface antigen CD24 (approximately 240 bp) was introduced into a myeloproliferative sarcoma virus (MPSV)-based retroviral vector, which was then… (More)

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@article{Pawliuk1994SelectionOR, title={Selection of retrovirally transduced hematopoietic cells using CD24 as a marker of gene transfer.}, author={Robert Pawliuk and Robert J. Kay and P L Lansdorp and Richard Keith Humphries}, journal={Blood}, year={1994}, volume={84 9}, pages={2868-77} }