Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant.

@article{Ballen2012SelectionOO,
  title={Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant.},
  author={Karen Kuhn Ballen and John Koreth and Yi-bin Chen and Bimalangshu R. Dey and Thomas R. Spitzer},
  journal={Blood},
  year={2012},
  volume={119 9},
  pages={1972-80}
}
Only 30% of patients who require an allogeneic hematopoietic cell transplant will have an HLA-matched sibling donor. A search for an unrelated donor will be undertaken for patients without a matched family donor. However, many patients, particularly patients of diverse racial and ethnic backgrounds, may not be able to rapidly identify a suitably matched unrelated donor. Three alternative graft sources, umbilical cord blood (UCB), haploidentical (haplo)-related donor, and mismatched unrelated… CONTINUE READING
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