Selection of nonfastidious adenovirus species in 293 cells inoculated with stool specimens containing adenovirus 40.

@article{Brown1985SelectionON,
  title={Selection of nonfastidious adenovirus species in 293 cells inoculated with stool specimens containing adenovirus 40.},
  author={Martha W Brown},
  journal={Journal of clinical microbiology},
  year={1985},
  volume={22 2},
  pages={
          205-9
        }
}
Of 35 stool specimens isolated and examined in 293 cells, 15 isolates contained adenovirus species 40 (Ad40), and 4 of these 15 isolates also contained a nonfastidious adenovirus species (Ad1 in two cases, Ad18 or Ad31) which was selected over Ad40 during serial passage in the 293 cells. The selection of Ad1 over Ad40 was examined in detail. Restriction analysis of intracellular DNA and the relative infectivity titers of Ad40 and Ad1 at each passage level after the inoculation of 293 cells with… CONTINUE READING

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F. L. Graham, J. Sniiley, W. C. Russe, R. Nairn
J. Gen. Virol. 36:59-72 • 1977
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