Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.

@article{Villet2006SelectionOA,
  title={Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.},
  author={St{\'e}phanie Villet and Christian Pichoud and J. Villeneuve and Christian Tr{\'e}po and Fabien Zoulim},
  journal={Gastroenterology},
  year={2006},
  volume={131 4},
  pages={1253-61}
}
BACKGROUND & AIMS Sequential anti-hepatitis B virus (HBV) therapy may lead to the selection of complex mutants. We analyzed the genetic and phenotypic evolution of the viral quasispecies of a patient who received successively lamivudine, add-on adefovir+lamivudine, followed by lamivudine+adefovir+hepatitis B immunoglobulins (HBIg) after orthotopic liver… CONTINUE READING