Selection of Astaxanthin-Overproducing Mutants of Phaffia rhodozyma with beta-Ionone.

  title={Selection of Astaxanthin-Overproducing Mutants of Phaffia rhodozyma with beta-Ionone.},
  author={Mark J. Lewis and Nicolas Ragot and M C Berlant and Michele Miranda},
  journal={Applied and environmental microbiology},
  volume={56 9},
beta-Ionone, an end ring analog of beta-carotene, inhibits astaxanthin production in the red yeast Phaffia rhodozyma. Astaxanthin-overproducing mutants of this yeast are easily spotted on beta-ionone-containing yeast malt agar plates. beta-Ionone appears to block astaxanthin synthesis at the beta-carotene level. 

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