Selection maintains MHC diversity through a natural population bottleneck.

  title={Selection maintains MHC diversity through a natural population bottleneck.},
  author={Matthew Kenneth Oliver and Stuart B. Piertney},
  journal={Molecular biology and evolution},
  volume={29 7},
A perceived consequence of a population bottleneck is the erosion of genetic diversity and concomitant reduction in individual fitness and evolutionary potential. Although reduced genetic variation associated with demographic perturbation has been amply demonstrated for neutral molecular markers, the effective management of genetic resources in natural populations is hindered by a lack of understanding of how adaptive genetic variation will respond to population fluctuations, given these are… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 33 extracted citations

Microevolution of bank voles (Myodes glareolus) at neutral and immune-related genes during multiannual dynamic cycles: Consequences for Puumala hantavirus epidemiology.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases • 2017
View 3 Excerpts


Publications referenced by this paper.
Showing 1-10 of 59 references

Selection for heterozygotes in small populations.

Genetics • 1962
View 6 Excerpts
Highly Influenced

MHC diversity in bottlenecked populations: a simulation model

Conservation Genetics • 2009
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…