Selection for high voluntary wheel-running increases speed and intermittency in house mice (Mus domesticus).

@article{Girard2001SelectionFH,
  title={Selection for high voluntary wheel-running increases speed and intermittency in house mice (Mus domesticus).},
  author={I A Girard and Michael McAleer and Justin S Rhodes and Theodore Garland},
  journal={The Journal of experimental biology},
  year={2001},
  volume={204 Pt 24},
  pages={4311-20}
}
In nature, many animals use intermittent rather than continuous locomotion. In laboratory studies, intermittent exercise regimens have been shown to increase endurance compared with continuous exercise. We hypothesized that increased intermittency has evolved in lines of house mice (Mus domesticus) that have been selectively bred for high voluntary wheel-running (wheel diameter 1.12 m) activity. After 23 generations, female mice from four replicate selection lines ran 2.7 times more revolutions… CONTINUE READING
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