Selection bias: maintaining less-differentiated T cells for adoptive immunotherapy.


The clinical application of T cell immunotherapy depends on ex vivo modification and expansion of T cells for adoptive transfer. In preclinical models, the use of a purified, naive T cell subset enhances persistence and antitumor immunity; however, the majority of clinical studies rely on modification of mixed populations of T cells that contain only a… (More)
DOI: 10.1172/JCI85631


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics