Selection as Driving Force in Lung and R on Carcinogenesis

Abstract

Downlo cinogenesis is the result of mutations and subsequent clonal expansions of mutated, selectively advans cells. To investigate the relative contributions of mutation versus cell selection in tumorigenesis, we red two mathematical models of carcinogenesis in two different cancer types: lung and colon. One ach is based on a population genetics model, the… (More)

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