Selection and characterization of single domain antibodies against human CD20.

Abstract

CD20 is a membrane protein with four integral membrane regions and a large extracellular loop between residues 142 and 187, which serves as a target binding region for rituximab (RTX) and most other anti-CD20 monoclonal antibodies. It is highly expressed in B-lymphoma cells and B lymphocytes and often serves as a target for immunotherapy. In this study, we… (More)
DOI: 10.1016/j.molimm.2016.09.013

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Cite this paper

@article{Liu2016SelectionAC, title={Selection and characterization of single domain antibodies against human CD20.}, author={Jinny L. Liu and Dan Zabetakis and Ellen R. Goldman and George P. Anderson}, journal={Molecular immunology}, year={2016}, volume={78}, pages={146-154} }