Selection Signature Analysis Implicates the PC1/PCSK1 Region for Chicken Abdominal Fat Content

@inproceedings{Zhang2012SelectionSA,
  title={Selection Signature Analysis Implicates the PC1/PCSK1 Region for Chicken Abdominal Fat Content},
  author={Hui Zhang and Xiao Xiang Hu and Zhipeng Wang and Yuandan Zhang and Shou-zhi Wang and Ning Wang and Li Ma and Li Leng and Shengwen Wang and Qigui Wang and Yuxiang Wang and Zhiquan Tang and Ning Li and Yang Da and Hui Li},
  booktitle={PloS one},
  year={2012}
}
We conducted a selection signature analysis using the chicken 60k SNP chip in two chicken lines that had been divergently selected for abdominal fat content (AFC) for 11 generations. The selection signature analysis used multiple signals of selection, including long-range allele frequency differences between the lean and fat lines, long-range heterozygosity changes, linkage disequilibrium, haplotype frequencies, and extended haplotype homozygosity. Multiple signals of selection identified ten… CONTINUE READING
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