Selecting, accelerating and suppressing interactions between macrophages and tumor cells.

@article{Baetselier1985SelectingAA,
  title={Selecting, accelerating and suppressing interactions between macrophages and tumor cells.},
  author={Patrick de Baetselier and Ahuva Kapon and Shulamit Katzav and Esther Tzehoval and Daniel Dekegel and Shraga Segal and Michael Feldman},
  journal={Invasion & metastasis},
  year={1985},
  volume={5 2},
  pages={106-24}
}
Studies were carried out to test whether thioglycollate-induced macrophages (T-PM phi) exert a selective effect on 3LL tumor cells. One million 3LL tumor cells and 10 X 10(6) thioglycollate-elicited peritoneal macrophages were admixed and inoculated subcutaneously in C57BL/6 mice. This procedure was repeated for a series of 6-15 consecutive transplant generations. After 6 generations, the tumor cells which were selected in this manner (3LLR6) grew faster in vivo and in vitro when admixed with T… CONTINUE READING

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