Selectin inhibitors: a patent review.

  title={Selectin inhibitors: a patent review.},
  author={Patricia W Bedard and Neelu Kaila},
  journal={Expert opinion on therapeutic patents},
  volume={20 6},
IMPORTANCE OF THE FIELD Selectins play a significant and well-documented role in inflammation and immune response. They initiate tethering and rolling of blood borne leukocytes leading to their activation, adhesion and subsequent extravazation into tissues. This is important for healthy immune response and tissue repair. However, dysregulation of selectins leads to exacerbation of disease. Atherosclerosis, restenosis, deep venous thrombosis and tumor metastasis are just a few of the diseases in… CONTINUE READING
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a patent review 792 Expert Opin

  • MW Saif, E Tytler, +5 authors for the treatment of Selectin inhibitors
  • Ther. Patents
  • 2010
1 Excerpt

Charité Universitaetsmedizin. Dendritic polyglycerol sulfates and sulfonates and their use for inflammatory diseases

  • Freie Uni Berlin
  • 2008
1 Excerpt

Crystalline forms of 1,6-bis [3-(3carboxymethylphenyl)-4-(2-alpha-dmannopyranosyl-oxy)-phenyl] hexane

  • AG RevotarBiopharmaceuticals
  • 2008
1 Excerpt

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