Selected major risk factors and global and regional burden of disease

@article{Ezzati2002SelectedMR,
  title={Selected major risk factors and global and regional burden of disease},
  author={Majid Ezzati and Alan D. Lopez and Anthony Rodgers and Stephen vander Hoorn and Christopher J. L. Murray},
  journal={The Lancet},
  year={2002},
  volume={360},
  pages={1347-1360}
}

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References

SHOWING 1-10 OF 66 REFERENCES

Global burden of disease and injury due to occupational factors.

TLDR
Estimates of absolute morbidity and mortality due to occupational factors for the world using all available published data as of 1994 are regarded as very conservative estimates which can nevertheless provide a basis for health priority planning at global level.

On the comparable quantification of health risks: lessons from the Global Burden of Disease Study.

TLDR
It is recommended that future assessments should focus on avoidable and attributable burden based on the plausible minimum risk counterfactual distribution of exposure, and four types of distributions of exposure that could be used as thecounterfactual distributions are identified.

The relation between funding by the National Institutes of Health and the burden of disease.

TLDR
A cross-sectional study comparing estimates of disease-specific funding in 1996 with data on six measures of the burden of disease found that the acquired immunodeficiency syndrome, breast cancer, diabetes mellitus, and dementia all received relatively generous funding, regardless of which measure was used as the basis for calculating support.

How much global ill health is attributable to environmental factors?

TLDR
The estimate is that 25-33% of the global burden of disease can be attributed to environmental risk factors, and children under 5 years of age seem to bear the largest environmental burden, and the portion of disease due to environmental risks seems to decrease with economic development.

Smoking vs other risk factors as the cause of smoking-attributable deaths: confounding in the courtroom.

TLDR
This study suggests that federal estimates of deaths caused by smoking are not substantially altered by adjustment for behavioral and demographic factors associated with smoking beyond the current adjustment for age and sex.

Actual causes of death in the United States.

TLDR
The most prominent contributors to mortality in the United States in 1990 were tobacco, diet and activity patterns, alcohol, microbial agents, toxic agents, firearms, sexual behavior, motor vehicles, and illicit use of drugs.

Alcohol and coronary heart disease: a meta-analysis.

TLDR
The degree of protection from moderate doses of alcohol should be reconsidered and the effect of drinking patterns on the risk of coronary heart disease should be performed, and caution is needed in making general recommendations.

Mortality from tobacco in developed countries: are indirect estimates reliable?

  • P. Lee
  • Medicine
    Regulatory toxicology and pharmacology : RTP
  • 1996
TLDR
The various assumptions on which the derivation of smoking-attributed deaths depends are described and discussed and it is shown that they are unlikely to hold in practice.
...