Selected MicroRNAs Define Cell Fate Determination of Murine Central Memory CD8 T Cells

@inproceedings{Almanza2010SelectedMD,
  title={Selected MicroRNAs Define Cell Fate Determination of Murine Central Memory CD8 T Cells},
  author={Gonzalo Almanza and Antonio Fern{\'a}ndez and Stefano Volinia and Xochitl Cortez-Gonzalez and Carlo M. Croce and Maurizio Zanetti},
  booktitle={PloS one},
  year={2010}
}
During an immune response T cells enter memory fate determination, a program that divides them into two main populations: effector memory and central memory T cells. Since in many systems protection appears to be preferentially mediated by T cells of the central memory it is important to understand when and how fate determination takes place. To date, cell intrinsic molecular events that determine their differentiation remains unclear. MicroRNAs are a class of small, evolutionarily conserved… CONTINUE READING
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