Select Listeria monocytogenes subtypes commonly found in foods carry distinct nonsense mutations in inlA, leading to expression of truncated and secreted internalin A, and are associated with a reduced invasion phenotype for human intestinal epithelial cells.

@article{Nightingale2005SelectLM,
  title={Select Listeria monocytogenes subtypes commonly found in foods carry distinct nonsense mutations in inlA, leading to expression of truncated and secreted internalin A, and are associated with a reduced invasion phenotype for human intestinal epithelial cells.},
  author={Kendra Kerr Nightingale and Katy Windham and Kiri E Martin and M. Yeung and Martin Wiedmann},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 12},
  pages={8764-72}
}
The surface protein internalin A (InlA) contributes to the invasion of human intestinal epithelial cells by Listeria monocytogenes. Screening of L. monocytogenes strains isolated from human clinical cases (n=46), foods (n=118), and healthy animals (n=58) in the United States revealed mutations in inlA leading to premature stop codons (PMSCs) in L. monocytogenes ribotypes DUP-1052A and DUP-16635A (PMSC mutation type 1), DUP-1025A and DUP-1031A (PMSC mutation type 2), and DUP-1046B and DUP-1062A… CONTINUE READING

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Liste­ riosis in the pregnant guinea pig: a model of vertical transmission

A. I. Barkardjiev, B. A. Stacy, S. J. Fisher, D. A. Portnoy
Infect. Immun • 2004

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