Select Dietary Phytochemicals Function as Inhibitors of COX-1 but Not COX-2

@inproceedings{Li2013SelectDP,
  title={Select Dietary Phytochemicals Function as Inhibitors of COX-1 but Not COX-2},
  author={Haitao Li and Feng Zhu and Yanwen Sun and Bing Nan Li and Naomi Oi and Hanyong Chen and Ronald A. Lubet and Ann M. Bode and Ziming Dong},
  booktitle={PloS one},
  year={2013}
}
Recent clinical trials raised concerns regarding the cardiovascular toxicity of selective cyclooxygenase-2 (COX-2) inhibitors. Many active dietary factors are reported to suppress carcinogenesis by targeting COX-2. A major question was accordingly raised: why has the lifelong use of phytochemicals that likely inhibit COX-2 presumably not been associated… CONTINUE READING