Select 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors vary in their ability to reduce egg yolk cholesterol levels in laying hens through alteration of hepatic cholesterol biosynthesis and plasma VLDL composition.

Abstract

The inability to markedly attenuate cholesterol levels in chicken eggs has led to speculation that cholesterol is essential for yolk formation and that egg production would cease when yolk cholesterol deposition was inadequate for embryonic survival. However, this critical level hypothesis remains unproven. Here, we determine the relative responsiveness of… (More)

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@article{Elkin1999Select3A, title={Select 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors vary in their ability to reduce egg yolk cholesterol levels in laying hens through alteration of hepatic cholesterol biosynthesis and plasma VLDL composition.}, author={Rena Elkin and Z. Yan and Y. Zhong and Shawn S. Donkin and Kimberly K. Buhman and James Story and J. J. Turek and Rebecca E Porter and M. Anderson and R. Homan and R. S. Newton}, journal={The Journal of nutrition}, year={1999}, volume={129 5}, pages={1010-9} }