Selección de antipsicóticos en un hospital psiquiátrico basada en los resultados del estudio CATIE

  title={Selecci{\'o}n de antipsic{\'o}ticos en un hospital psiqui{\'a}trico basada en los resultados del estudio CATIE},
  author={Felicitas Guti{\'e}rrez-Suela},
  journal={Farmacia Hospitalaria},

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Nuevas perspectivas en la psicopatología de los trastornos esquizofréni- cos New perspectives on the psychopathology of schizophrenic disorders
Present tendencies in psychopathological research into schizophrenia are delimited, with the advantage offered by dimensional approaches.
Evolución de los patrones de tratamiento de los pacientes esquizofrénicos
It is concluded that the atypical neurolePTics are becoming established in the treatment of schizophrenia, although they have not so far displaced conventional neuroleptics.
Effectiveness of Olanzapine, Quetiapine, Risperidone, and Ziprasidone in Patients With Chronic Schizophrenia Following Discontinuation of a Previous Atypical Antipsychotic
If there were differences between these four treatments in effectiveness measured by time until discontinuation for any reason, this randomized, double-blind study compared them in patients who had just discontinued a different atypical antipsychotic.
Effectiveness and cost of olanzapine and haloperidol in the treatment of schizophrenia: a randomized controlled trial.
Olanzapine does not demonstrate advantages compared with haloperidol (in combination with prophylactic benztropine) in compliance, symptoms, extrapyramidal symptoms, or overall quality of life, and its benefits in reducing akathisia and improving cognition must be balanced with the problems of weight gain and higher cost.
Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic.
Among this group of patients with chronic schizophrenia who had just discontinued treatment with an atypical antipsychotic, risperidone and olanzapine were more effective than quetiapine and ziprasidone as reflected by longer time until discontinuation for any reason.
Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment.
For patients with schizophrenia who prospectively failed to improve with an atypical antipsychotic, clozapine was more effective than switching to another newer atypicals antipsychotics.
Amisulpride, an unusual "atypical" antipsychotic: a meta-analysis of randomized controlled trials.
These results cast some doubt on the notion that combined 5-HT(2)/D(2) antagonism is the reason that the newer antipsychotic medications are effective for negative symptoms and have fewer extrapyramidal side effects.
Negative symptoms: a path analytic approach to a double-blind, placebo- and haloperidol-controlled clinical trial with olanzapine.
The results suggest that the negative symptoms of schizophrenia are directly responsive to treatment, and contribute to the hypothesis that negative symptoms may be under the influence of several neurotransmitters within one or more neuroanatomic circuits.
A Meta-analysis of the Efficacy of Second-Generation Antipsychotics
Some SGAs are more efficacious than FGAs, and, therefore,SGAs are not a homogeneous group, as suggested by consensus panel recommendations.
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.
Olanzapine was the most effective in terms of the rates of discontinuation, and the efficacy of the conventional antipsychotic agent perphenazine appeared similar to that of quetiapine, risperidone, and ziprasidone.