Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long‐term video‐EEG monitoring in the rat
@article{Raedt2009SeizuresIT, title={Seizures in the intrahippocampal kainic acid epilepsy model: characterization using long‐term video‐EEG monitoring in the rat}, author={R. Raedt and A. Van Dycke and D. Van Melkebeke and T. De Smedt and P. Claeys and T. Wyckhuys and K. Vonck and W. Wadman and P. Boon}, journal={Acta Neurologica Scandinavica}, year={2009}, volume={119} }
Objective – Intrahippocampal injection of kainic acid (KA) in rats evokes a status epilepticus (SE) and leads to spontaneous seizures. However to date, precise electroencephalographic (EEG) and clinical characterization of spontaneous seizures in this epilepsy model using long‐term video‐EEG monitoring has not been performed.
Topics from this paper
73 Citations
Variable electrobehavioral patterns during focal nonconvulsive status epilepticus induced by unilateral intrahippocampal injection of kainic acid
- Medicine
- Epilepsia
- 2014
- 7
A guinea pig model of mesial temporal lobe epilepsy following nonconvulsive status epilepticus induced by unilateral intrahippocampal injection of kainic acid
- Medicine
- Epilepsia
- 2012
- 27
Immediate Epileptogenesis after Kainate-Induced Status Epilepticus in C57BL/6J Mice: Evidence from Long Term Continuous Video-EEG Telemetry
- Medicine
- PloS one
- 2015
- 33
- PDF
Various modifications of the intrahippocampal kainate model of mesial temporal lobe epilepsy in rats fail to resolve the marked rat-to-mouse differences in type and frequency of spontaneous seizures in this model
- Psychology, Medicine
- Epilepsy & Behavior
- 2017
- 10
Seizure frequency in pilocarpine‐treated rats is independent of circadian rhythm
- Medicine
- Epilepsia
- 2011
- 32
- Highly Influenced
The systemic kainic acid rat model of temporal lobe epilepsy: Long-term EEG monitoring
- Psychology, Medicine
- Brain Research
- 2015
- 33
- Highly Influenced
The intrahippocampal kainate model of temporal lobe epilepsy revisited: Epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats
- Medicine, Psychology
- Epilepsy Research
- 2013
- 62
A novel animal model of acquired human temporal lobe epilepsy based on the simultaneous administration of kainic acid and lorazepam
- Psychology, Medicine
- Epilepsia
- 2017
- 14
The kainic acid model of temporal lobe epilepsy
- Psychology, Medicine
- Neuroscience & Biobehavioral Reviews
- 2013
- 255
- Highly Influenced
References
SHOWING 1-10 OF 62 REFERENCES
Analysis of Chronic Seizure Onsets after Intrahippocampal Kainic Acid Injection in Freely Moving Rats
- Medicine
- Epilepsia
- 2005
- 160
On the relation between seizures and brain lesions after intracerebroventricular kainic acid
- Medicine
- Neuroscience Letters
- 1988
- 42
Electrophysiologic Analysis of a Chronic Seizure Model After Unilateral Hippocampal KA Injection
- Psychology, Medicine
- Epilepsia
- 1999
- 254
- Highly Influential
Behavioral, Morphologic, and Electroencephalographic Evaluation of Seizures Induced by Intrahippocampal Microinjection of Pilocarpine
- Medicine
- Epilepsia
- 2002
- 83
- Highly Influential
Kainic acid induced hippocampal seizures in rats: comparisons of acute and chronic seizures using intrahippocampal versus systemic injections
- Medicine
- The Italian Journal of Neurological Sciences
- 2005
- 26
Kainic acid seizures in the developing brain: status epilepticus and spontaneous recurrent seizures.
- Medicine
- Brain research. Developmental brain research
- 1992
- 290
Spontaneous motor seizures of rats with kainate-induced epilepsy: effect of time of day and activity state
- Psychology, Medicine
- Epilepsy Research
- 1999
- 90
Hippocampal damage after injection of kainic acid into the rat entorhinal cortex
- Biology, Medicine
- Brain Research
- 1998
- 28
Intrahippocampal kainic acid, seizures and local neuronal degeneration: Relationships assessed in unanesthetized rats
- Chemistry, Medicine
- Neuroscience
- 1982
- 88
High‐frequency Oscillations after Status Epilepticus: Epileptogenesis and Seizure Genesis
- Medicine
- Epilepsia
- 2004
- 302
- Highly Influential