Seizures and epilepsy in herpes simplex virus encephalitis: current concepts and future directions of pathogenesis and management

@article{Sellner2012SeizuresAE,
  title={Seizures and epilepsy in herpes simplex virus encephalitis: current concepts and future directions of pathogenesis and management},
  author={Johann Sellner and Eugen Trinka},
  journal={Journal of Neurology},
  year={2012},
  volume={259},
  pages={2019-2030}
}
Mortality related to herpes simplex virus encephalitis (HSE) dropped dramatically with the systematic initiation of antiviral treatment in encephalitic syndromes. Further efforts need to be taken to reduce long-term morbidity in the survivors. In this regard, the high rate of postencephalitic epilepsy, which is frequently refractory to medical treatment, contributes significantly to the unfavorable clinical outcome of the disease. Seizures during the acute phase of HSE are the main risk for the… 

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