Seizures, but not lowered seizure thresholds, results in larger neocortical motor maps and concomitant disruptions in skilled motor behaviour.

@article{Flynn2010SeizuresBN,
  title={Seizures, but not lowered seizure thresholds, results in larger neocortical motor maps and concomitant disruptions in skilled motor behaviour.},
  author={Corey Flynn and Nicole A. Young and G. Campbell Teskey},
  journal={Behavioural brain research},
  year={2010},
  volume={214 1},
  pages={60-5}
}
Kindling of the sensorimotor neocortex has been found to result in reorganization of the somatotopic map of movement representations as well as disruptions of skilled forelimb behaviours. It has been suggested that the repeated seizures induced during kindling altered motor maps, thereby disrupting the motor engram necessary for the production of skilled movements. However, kindling leads to neural changes other than those associated with repeated seizures, and the role of these comorbid… CONTINUE READING
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Reducing seizure thresholdwithelectrical stimulation leads to increased perforated synapses

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