Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet.

@article{Bough1999SeizureRI,
  title={Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet.},
  author={Kristopher J Bough and Ritu Valiyil and Frederick T. Han and Douglas A. Eagles},
  journal={Epilepsy research},
  year={1999},
  volume={35 1},
  pages={21-8}
}
The present study was designed to evaluate the effects of age on the efficacy of the ketogenic diet in suppressing seizures evoked by tail-vein infusion of pentylenetetrazole (PTZ). Male rats of various ages were divided into three groups and fed one of three diets: (1) a calorie-restricted ketogenic diet, (2) a calorie-restricted normal (rodent chow) diet, or (3) a normal diet, ad libitum. After animals had been on experimental or control diets for more than 20 days, seizure threshold and… CONTINUE READING
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