Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus

@article{Holmes2002SeizureinducedMI,
  title={Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus},
  author={Gregory L. Holmes and Yili Yang and Zhao Liu and Jennifer Marie Cermak and Jan Krzysztof Blusztajn},
  journal={Epilepsy Research},
  year={2002},
  volume={48},
  pages={3-13}
}
Prenatal choline supplementation can protect rats against cognitive deficits induced by status epilepticus induced by the cholinergic agent pilocarpine [J. Neurosci. 20 (2000) 1]. In the present day, we have extended this novel finding by investigating the effects of pre- and postnatal choline supplementation in memory deficits associated with status epilepticus induced with kainic acid (KA). In the first experiment pregnant rats received a normal, choline-supplemented, or choline deficient… CONTINUE READING

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