Seizure frequency and characteristics in children with Down syndrome

  title={Seizure frequency and characteristics in children with Down syndrome},
  author={Hadassa Goldberg-Stern and Richard H Strawsburg and Bonnie Patterson and Fran Hickey and Ton J. Degrauw},
  journal={Brain and Development},
Seizures have not historically been considered a major component of Down syndrome. We examined the prevalence of epileptic seizures in 350 children and adolescents with Down syndrome evaluated at a regional center between 1985 and 1997. Results showed that 28 patients (8%) had epileptic seizures: 13 (47%) partial seizures; 9 (32%) infantile spasms, and 6 (21%) generalized tonic-clonic seizures. In the infantile spasm group, there was no relationship between the initial electroencephalogram (EEG… CONTINUE READING


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