Seizure clusters: A common, understudied and undertreated phenomenon in refractory epilepsy

@article{Komaragiri2016SeizureCA,
  title={Seizure clusters: A common, understudied and undertreated phenomenon in refractory epilepsy},
  author={Arpitha Komaragiri and Kamil Detyniecki and Lawrence J. Hirsch},
  journal={Epilepsy \& Behavior},
  year={2016},
  volume={59},
  pages={83-86}
}

Frequency of Seizure Clusters and Their Associated Risk Factors in Adult Patients with Epilepsy Referred to Epilepsy Center of Kashani Hospital in Isfahan from 2011 to 2016

Important risk factors that are found to be associated are age of onset, parental consanguinity, frequency of seizure, lack of have seizure-free period or periods, pathologies in neurological examination, and MRI findings.

Factors predisposing patients with temporal lobe epilepsy to seizure cluster

In patients with TLE, seizure clustering had no correlation with the epilepsy duration, the amount of IEDs, or brain MRI findings.

The Occurrence of Seizure Clusters in Patients With Epilepsy Is Partly Determined by Epilepsy Severity: A Single-Center Retrospective Observational Study

Seizure clusters (SCs) are common occurrences at the study center, and the occurrence of SC in individuals with epilepsy, to some extent, is determined by the epilepsy severity.

The correlation between cluster seizures and findings of magnetic resonance imaging in drug refractory epilepsy patients.

According to results of this study it seems that brain MRI findings of drug refractory epilepsy patients with a history of seizure clusters are different from brainMRI findings ofDrug Refractory Epilepsy patients without a historyof seizure clusters.

Updated review of rescue treatments for seizure clusters and prolonged seizures

Clinical opportunities for rescue medications, with particular attention focused on seizure clusters and prolonged seizures, are discussed, including their epidemiology, risk factors, and associated morbidity.

A critical evaluation of midazolam nasal spray for the treatment of patients with seizure clusters

  • J. Wheless
  • Medicine
    Expert review of neurotherapeutics
  • 2021
A critical evaluation of MDZ-NS for the treatment of patients with SCs is provided, which offers the benefits of intranasal administration, which allows for outpatient treatment by caregivers and other non-healthcare professionals when an SC occurs, and may be particularly meaningful to patients with limited treatment options because other routes of administration are unsuitable.

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