Seizure cluster: Definition, prevalence, consequences, and management

@article{Jafarpour2019SeizureCD,
  title={Seizure cluster: Definition, prevalence, consequences, and management},
  author={Saba Jafarpour and Lawrence J. Hirsch and Marina Ga{\'i}nza-Lein and Christoph Kellinghaus and Kamil Detyniecki},
  journal={Seizure},
  year={2019},
  volume={68},
  pages={9-15}
}

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References

SHOWING 1-10 OF 85 REFERENCES

Seizure clusters: characteristics and treatment.

  • S. Haut
  • Medicine
    Current opinion in neurology
  • 2015
Progress towards the development of nonintravenous routes of benzodiazepines has the potential to improve care in this area and greater focus on clarifying of definition and clinical implications is required.

Does Seizure Duration Predict the Termination of a Seizure Cluster?

High percentage of seizure clusters were found in medically intractable patients monitored in the epilepsy monitoring unit for presurgical evaluation, and the authors paid special attention to the last seizure of the cluster, which they termed the “terminal seizure.

Seizure clusters in drug‐resistant focal epilepsy

It is found that seizure clusters relate to prognosis after temporal lobe surgery in drug‐resistant TLE and may provide added value for surgical prognostication when combined with other data types.

Seizure clustering during drug treatment affects seizure outcome and mortality of childhood-onset epilepsy.

Cl clustering of seizures during treatment, but not prior to treatment, is associated with a poorer long-term seizure and mortality outcome, and patients with seizure clustering prior to, butNot during, treatment versus those with no clustering showed no difference in seizure outcome or mortality risk.

Epilepsy: accuracy of patient seizure counts.

Patient seizure counts do not provide valid information and Unchanged documentation accuracy is a prerequisite for the use of patient seizure counts in clinical trials and has to be demonstrated in a subsample of patients undergoing electroencephalographic monitoring.

Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring

Although status epilepticus is uncommon at epilepsy monitoring units, clusters of seizures are common, and intensive monitoring with drug withdrawal must be performed in a highly supervised, hospitalized setting.

Timing of Seizure Recurrence in Adult Epileptic Patients: A Statistical Analysis

The observations indicate that seizure cycling and/or clustering are not common in epileptic patients, but do not exclude the possibility that seizures have been precipitated by some randomly occurring event, such as sleep deprivation or increased stress.
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