Segregation of the Qb-SNAREs GS27 and GS28 into Golgi vesicles regulates intra-Golgi transport.

@article{Fusella2013SegregationOT,
  title={Segregation of the Qb-SNAREs GS27 and GS28 into Golgi vesicles regulates intra-Golgi transport.},
  author={Aurora Fusella and Massimo Micaroni and Daniele Di Giandomenico and Alexandre A. Mironov and Galina V. Beznoussenko},
  journal={Traffic},
  year={2013},
  volume={14 5},
  pages={568-84}
}
The Golgi apparatus is the main glycosylation and sorting station along the secretory pathway. Its structure includes the Golgi vesicles, which are depleted of anterograde cargo, and also of at least some Golgi-resident proteins. The role of Golgi vesicles remains unclear. Here, we show that Golgi vesicles are enriched in the Qb-SNAREs GS27 (membrin) and GS28 (GOS-28), and depleted of nucleotide sugar transporters. A block of intra-Golgi transport leads to accumulation of Golgi vesicles and… CONTINUE READING
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